Ulcerative colitis—Maintanance of Remission With the Probiotic Escherichia coli Strain Nissle 1917
نویسندگان
چکیده
منابع مشابه
Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine
Background and aim: Evidence exists for the pathogenic role of the enteric flora in inflammatory bowel disease. Probiotics contain living microorganisms which exert health effects on the host. We compared the efficacy in maintaining remission of the probiotic preparation Escherichia coli Nissle 1917 and established therapy with mesalazine in patients with ulcerative colitis. Patients and method...
متن کامل[Maintaining remission of ulcerative colitis with the probiotic Escherichia Coli Nissle 1917 is as effective as with standard mesalazine].
BACKGROUND AND AIMS Evidence exists for the pathogenic role of the enteric flora in inflammatory bowel disease. Probiotics contain living microorganisms which exert health effects on the host. We compared the efficacy in maintaining remission of the probiotic preparation Escherichia coli Nissle 1917 and established therapy with mesalazine in patients with ulcerative colitis. PATIENTS AND METH...
متن کاملAnalysis of the genome structure of the nonpathogenic probiotic Escherichia coli strain Nissle 1917.
Nonpathogenic Escherichia coli strain Nissle 1917 (O6:K5:H1) is used as a probiotic agent in medicine, mainly for the treatment of various gastroenterological diseases. To gain insight on the genetic level into its properties of colonization and commensalism, this strain's genome structure has been analyzed by three approaches: (i) sequence context screening of tRNA genes as a potential indicat...
متن کاملGenotoxicity of Escherichia coli Nissle 1917 strain cannot be dissociated from its probiotic activity
Oral administration of the probiotic bacterium Escherichia coli Nissle 1917 improves chronic inflammatory bowel diseases, but the molecular basis for this therapeutic efficacy is unknown. E. coli Nissle 1917 harbors a cluster of genes coding for the biosynthesis of hybrid nonribosomal peptide-polyketide(s). This biosynthetic pathway confers the ability for bacteria to induce DNA double strand b...
متن کاملProbiotic bacteria Escherichia coli strain Nissle 1917 attenuates acute gastric lesions induced by stress.
Probiotic bacteria Escherichia coli Nissle (EcN) was shown to prevent or heal acute murine colitis, but gastroprotective effects of EcN against mucosal injury have been little studied. In this study, the effects of EcN on formation of stress-induced gastric erosions were assessed in rats. Rats were divided in following treatment groups: 1) vehicle (control); 2) EcN 10(1) CFU/ml; 3) EcN 10(4) CF...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2021
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2020.12.040